Anti-Tumor necrosis factor receptor superfamily member 19 antibody (aa: 75-88) (STJA0040851)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeMixed
ImmunogenA synthetic peptide (CRPHRF KEDWGFQK) as part of mouse TROY protein (aa: 75-88) conjugated to the immunogenic protein Blue Carrier Protein
General Information
| Short Description | Rabbit polyclonal anti-Tumor necrosis factor receptor superfamily member 19 (aa: 75-88) for use in IHC-F in Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-F |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | Mixed |
| Conjugation | Unconjugated |
| Purification | Whole serum |
| Dilution Range | IHC 1:500-1:2000 |
| Storage Instruction | Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. After reconstitution keep aliquots at-20°C for a higher stability, and at 2-8°C with an appropriate antibacterial |
Target Information
| Gene Symbol | Tnfrsf19 |
| Gene ID | 29820 |
| Uniprot ID | TNR19_MOUSE |
| Immunogen | A synthetic peptide (CRPHRF KEDWGFQK) as part of mouse TROY protein (aa: 75-88) conjugated to the immunogenic protein Blue Carrier Protein |
| Immunogen Region | aa: 75-88 |
| Immunogen Sequence | Mouse |
| Specificity | Specificity for TROY was confirmed by IHC. This antiserum is known to react with rat TROY. Reactivity with other species have not yet been tested. |
Additional Info
| Tissue Specificity | Highly expressed in adult brain, and in embryos from day 11-17, but not earlier. Detected in embryonic brain and epithelium, and at lower levels in adult heart, lung and liver. In neonatal mice, mainly in hair follicles and neuron-like cells in the cerebellum, but not in the skin epidermis. Isoform 3 was found in embryonic day 17.5 skin but not in brain and liver. |
| Function | Can mediate activation of c-Jun and NF-kappa-B. May promote caspase-independent cell death. Isoform 2 and isoform 3 may act as decoy receptors. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 19TradeToxicity And Jnk Inducer |
| Database Links | |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 3: Cell MembraneIsoform 4: Cell MembraneIsoform 2: Secreted |
| Alternative Antibody Names | Anti-Tumor Necrosis Factor Receptor Superfamily Member 19 antibodyAnti-Trade antibodyAnti-Toxicity And Jnk Inducer antibodyAnti-Tnfrsf19 antibodyAnti-Taj antibodyAnti-Troy antibody |
Information sourced from Uniprot.org