Anti-TSPYL2 antibody (STJ191806)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-Testis-specific Y-encoded-like protein 2 for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TSPYL2 |
| Gene ID | 64061 |
| Uniprot ID | TSYL2_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | TSYL2 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Post Translational Modifications | Phosphorylation at Ser-20 and/or Thr-340 impairs function on cell proliferation. |
| Function | Part of the CASK/TBR1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression. |
| Protein Name | Testis-Specific Y-Encoded-Like Protein 2Tspy-Like Protein 2Cell Division Autoantigen 1Cutaneous T-Cell Lymphoma-Associated Antigen Se20-4Ctcl-Associated Antigen Se20-4Differentially-Expressed Nucleolar Tgf-Beta1 Target ProteinNuclear Protein Of 79 KdaNp79 |
| Database Links | Reactome: R-HSA-381038 |
| Cellular Localisation | NucleusCytoplasmEnriched In Transcriptionally Active Regions Of Chromatin In Neurons |
| Alternative Antibody Names | Anti-Testis-Specific Y-Encoded-Like Protein 2 antibodyAnti-Tspy-Like Protein 2 antibodyAnti-Cell Division Autoantigen 1 antibodyAnti-Cutaneous T-Cell Lymphoma-Associated Antigen Se20-4 antibodyAnti-Ctcl-Associated Antigen Se20-4 antibodyAnti-Differentially-Expressed Nucleolar Tgf-Beta1 Target Protein antibodyAnti-Nuclear Protein Of 79 Kda antibodyAnti-Np79 antibodyAnti-TSPYL2 antibodyAnti-CDA1 antibodyAnti-DENTT antibodyAnti-TSPX antibodyAnti-HRIHFB2216 antibody |
Information sourced from Uniprot.org