Anti-TSPO antibody (90-170 aa) (STJ94977)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from PBR at the amino acid range 90-170
General Information
| Short Description | Rabbit polyclonal anti-Translocator protein (90-170 aa) for use in WB and IHC in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TSPO |
| Gene ID | 706 |
| Uniprot ID | TSPO_HUMAN |
| Immunogen | Synthesized peptide derived from PBR at the amino acid range 90-170 |
| Immunogen Region | 90-170 aa |
| Specificity | PBR Polyclonal Antibody detects endogenous levels of PBR protein. |
Additional Info
| Function | Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme. Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism, but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Was initially identified as peripheral-type benzodiazepine receptor.can also bind isoquinoline carboxamides. |
| Protein Name | Translocator ProteinMitochondrial Benzodiazepine ReceptorPkbsPeripheral-Type Benzodiazepine ReceptorPbr |
| Database Links | Reactome: R-HSA-196108 |
| Cellular Localisation | Mitochondrion MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Translocator Protein antibodyAnti-Mitochondrial Benzodiazepine Receptor antibodyAnti-Pkbs antibodyAnti-Peripheral-Type Benzodiazepine Receptor antibodyAnti-Pbr antibodyAnti-TSPO antibodyAnti-BZRP antibodyAnti-MBR antibody |
Information sourced from Uniprot.org