Anti-TSPAN15 antibody (STJA0009050)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human TSPAN15
General Information
| Short Description | Rabbit polyclonal anti-Tetraspanin-15 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TSPAN15 |
| Gene ID | 23555 |
| Uniprot ID | TSN15_HUMAN |
| Immunogen | Synthesized peptide derived from human TSPAN15 |
| Specificity | This antibody detects endogenous levels of TSPAN15 at Human, Mouse |
Additional Info
| Function | Part of TspanC8 subgroup, composed of 6 members that interact with the transmembrane metalloprotease ADAM10. This interaction is required for ADAM10 exit from the endoplasmic reticulum and for enzymatic maturation and trafficking to the cell surface as well as substrate specificity. Different TspanC8/ADAM10 complexes have distinct substrates. Promotes ADAM10-mediated cleavage of CDH2. Negatively regulates ligand-induced Notch activity probably by regulating ADAM10 activity. |
| Protein Name | Tetraspanin-15Tspan-15Tetraspan Net-7Transmembrane 4 Superfamily Member 15 |
| Database Links | Reactome: R-HSA-977225 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinLate Endosome Membrane |
| Alternative Antibody Names | Anti-Tetraspanin-15 antibodyAnti-Tspan-15 antibodyAnti-Tetraspan Net-7 antibodyAnti-Transmembrane 4 Superfamily Member 15 antibodyAnti-TSPAN15 antibodyAnti-NET7 antibodyAnti-TM4SF15 antibodyAnti-UNQ677 antibodyAnti-PRO1311 antibody |
Information sourced from Uniprot.org