Anti-TSHR/LGR3 antibody [1H7] (STJA0027784)

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STJA0027784-100
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Short Description :Mouse monoclonal Thyrotropin Receptor antibody for use in FC, Neut and WB in human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:FC/Neut/WB
Host:Mouse
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :1H7
Isotype:IgG1
Conjugation:Unconjugated
Concentration:1 mg/ml
Purification:Protein A/G purified from cell culture supernatant.
Formulation:0.01M PBS, pH 7.4, 0.09% Sodium azide.
Storage Instruction:Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol:TSHR
Gene ID:7253
Uniprot ID:TSHR_HUMAN
Post Translational Modifications Glycosylated. Sulfated. Sulfation on Tyr-385 plays a role in thyrotropin receptor binding and activation.
Function Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism.
Protein Name Thyrotropin Receptor
Thyroid-Stimulating Hormone Receptor
Tsh-R
Database Links Reactome: R-HSA-375281
Reactome: R-HSA-418555
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Basolateral Cell Membrane
Alternative Antibody Names Anti-Thyrotropin Receptor antibody
Anti-Thyroid-Stimulating Hormone Receptor antibody
Anti-Tsh-R antibody
Anti-TSHR antibody
Anti-LGR3 antibody

Information sourced from Uniprot.org

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