Anti-TSC22D4 antibody (STJA0008815)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human TSC22D4
General Information
| Short Description | Rabbit polyclonal anti-TSC22 domain family protein 4 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TSC22D4 |
| Gene ID | 81628 |
| Uniprot ID | T22D4_HUMAN |
| Immunogen | Synthesized peptide derived from human TSC22D4 |
| Specificity | This antibody detects endogenous levels of TSC22D4 at Human, Mouse, Rat |
Additional Info
| Function | Binds DNA and acts as a transcriptional repressor. Involved in the regulation of systematic glucose homeostasis and insulin sensitivity, via transcriptional repression of downstream insulin signaling targets such as OBP2A/LCN13. Acts as a negative regulator of lipogenic gene expression in hepatocytes and thereby mediates the control of very low-density lipoprotein release. May play a role in neurite elongation and survival. |
| Protein Name | Tsc22 Domain Family Protein 4Tsc22-Related-Inducible Leucine Zipper Protein 2 |
| Database Links | |
| Cellular Localisation | NucleusCytoplasmCell ProjectionDendriteSynapseLocalizes Away From The Nucleus To Neurite Processes And Synaptic Termini As Cerebellar Granular Neurons DifferentiateAccumulates In The Cytoplasm Of Differentiated Purkinje CellsLocalized To Both The Cytoplasm And Nucleus In Immature Cerebellar Granular Neurons And Atrophic Purkinje Cells |
| Alternative Antibody Names | Anti-Tsc22 Domain Family Protein 4 antibodyAnti-Tsc22-Related-Inducible Leucine Zipper Protein 2 antibodyAnti-TSC22D4 antibodyAnti-THG1 antibodyAnti-THG1-PIT antibody |
Information sourced from Uniprot.org