Anti-Tryptophan 5 Hydroxylase 1 antibody [R06-2J1] (STJA0035969)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human TPH1
General Information
| Short Description | Rabbit monoclonal anti-Tryptophan 5 Hydroxylase 1 for use in WB, IHC-P and IP in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IP |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R06-2J1 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100IP 1:50 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | TPH1 |
| Gene ID | 7166 |
| Uniprot ID | TPH1_HUMAN |
| Immunogen | A synthesized peptide derived from human TPH1 |
Additional Info
| Tissue Specificity | Isoform 2: Seems to be less widely expressed than isoform 1. |
| Post Translational Modifications | Ubiquitinated, leading to its degradation by the proteasome. Ubiquitinated is triggered by phosphorylation. Phosphorylated.triggering degradation by the proteasome. |
| Function | Oxidizes L-tryptophan to 5-hydroxy-l-tryptophan in the rate-determining step of serotonin biosynthesis. |
| Protein Name | Tryptophan 5-Hydroxylase 1Tryptophan 5-Monooxygenase 1 |
| Database Links | Reactome: R-HSA-209931Reactome: R-HSA-9031628 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Tryptophan 5-Hydroxylase 1 antibodyAnti-Tryptophan 5-Monooxygenase 1 antibodyAnti-TPH1 antibodyAnti-TPH antibodyAnti-TPRH antibodyAnti-TRPH antibody |
Information sourced from Uniprot.org