Anti-TRUB2 antibody [R08-5D1] (STJA0034958)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant protein of human TRUB2
General Information
| Short Description | Rabbit monoclonal anti-TRUB2 for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R08-5D1 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | TRUB2 |
| Gene ID | 26995 |
| Uniprot ID | TRUB2_HUMAN |
| Immunogen | Recombinant protein of human TRUB2 |
Additional Info
| Function | Minor enzyme contributing to the isomerization of uridine to pseudouridine (pseudouridylation) of specific mitochondrial mRNAs (mt-mRNAs) such as COXI and COXIII mt-mRNAs. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation. Also catalyzes pseudouridylation of some tRNAs, including synthesis of pseudouridine(55) from uracil-55, in the psi GC loop of a subset of tRNAs. |
| Protein Name | Pseudouridylate Synthase Trub2 - MitochondrialTrub Pseudouridine Synthase Homolog 2Trna Pseudouridine 55 Synthase Trub2Psi55 Synthase Trub2 |
| Database Links | |
| Cellular Localisation | Mitochondrion MatrixLocalizes To Mitochondrial Rna GranulesPlatforms For Post-Transcriptional Rna Modification And Ribosome Assembly |
| Alternative Antibody Names | Anti-Pseudouridylate Synthase Trub2 - Mitochondrial antibodyAnti-Trub Pseudouridine Synthase Homolog 2 antibodyAnti-Trna Pseudouridine 55 Synthase Trub2 antibodyAnti-Psi55 Synthase Trub2 antibodyAnti-TRUB2 antibody |
Information sourced from Uniprot.org