| Host: | Rabbit |
| Applications: | WB/IF/IP |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Transient receptor potential cation channel subfamily V member 2 (493-543 aa) is suitable for use in Western Blot, Immunofluorescence and Immunoprecipitation research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 IF ICC 1:100-500 IP 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TRPV2 |
| Gene ID: | 51393 |
| Uniprot ID: | TRPV2_HUMAN |
| Immunogen Region: | 493-543 aa |
| Specificity: | This antibody detects endogenous levels of TRPV2 at Human/Mouse/Rat |
| Immunogen: | Synthesized peptide derived from the human TRPV2 at the amino acid range 493-543 |
| Function | Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by IGF1, PDGF and neuropeptide head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius.is not activated by vanilloids and acidic pH. |
| Protein Name | Transient Receptor Potential Cation Channel Subfamily V Member 2 Trpv2 Osm-9-Like Trp Channel 2 Otrpc2 Vanilloid Receptor-Like Protein 1 Vrl-1 |
| Database Links | Reactome: R-HSA-3295583 |
| Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein Cytoplasm Melanosome Translocates From The Cytoplasm To The Plasma Membrane Upon Ligand Stimulation Identified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv |
| Alternative Antibody Names | Anti-Transient Receptor Potential Cation Channel Subfamily V Member 2 antibody Anti-Trpv2 antibody Anti-Osm-9-Like Trp Channel 2 antibody Anti-Otrpc2 antibody Anti-Vanilloid Receptor-Like Protein 1 antibody Anti-Vrl-1 antibody Anti-TRPV2 antibody Anti-VRL antibody |
Information sourced from Uniprot.org