| Host: |
Rabbit |
| Applications: |
IHC/IF/WB/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Zinc finger transcription factor Trps1 (121-170 aa) is suitable for use in Immunohistochemistry, Immunofluorescence, Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000IHC 1:100-1:300ELISA 1:5000IF 1:50-200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TRPS1 |
| Gene ID: |
7227 |
| Uniprot ID: |
TRPS1_HUMAN |
| Immunogen Region: |
121-170 aa |
| Specificity: |
TRPS1 Polyclonal Antibody detects endogenous levels of TRPS1 protein. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from the human TRPS1 at the amino acid range 121-170 |
| Post Translational Modifications | Sumoylated. Sumoylation in the repressor domain inhibits the transcription repression activity. Sumoylation on Lys-1201 is the major site. Appears to be sumoylated on multiple sites. |
| Function | Transcriptional repressor. Binds specifically to GATA sequences and represses expression of GATA-regulated genes at selected sites and stages in vertebrate development. Regulates chondrocyte proliferation and differentiation. Executes multiple functions in proliferating chondrocytes, expanding the region of distal chondrocytes, activating proliferation in columnar cells and supporting the differentiation of columnar into hypertrophic chondrocytes. |
| Protein Name | Zinc Finger Transcription Factor Trps1Tricho-Rhino-Phalangeal Syndrome Type I ProteinZinc Finger Protein Gc79 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Zinc Finger Transcription Factor Trps1 antibodyAnti-Tricho-Rhino-Phalangeal Syndrome Type I Protein antibodyAnti-Zinc Finger Protein Gc79 antibodyAnti-TRPS1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
