Anti-TRPS1 antibody (121-170 aa) (STJ96116)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human TRPS1 at the amino acid range 121-170
General Information
| Short Description | Rabbit polyclonal anti-Zinc finger transcription factor Trps1 (121-170 aa) for use in IHC, IF, WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF/WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC 1:100-1:300ELISA 1:5000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TRPS1 |
| Gene ID | 7227 |
| Uniprot ID | TRPS1_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human TRPS1 at the amino acid range 121-170 |
| Immunogen Region | 121-170 aa |
| Specificity | TRPS1 Polyclonal Antibody detects endogenous levels of TRPS1 protein. |
Additional Info
| Post Translational Modifications | Sumoylated. Sumoylation in the repressor domain inhibits the transcription repression activity. Sumoylation on Lys-1201 is the major site. Appears to be sumoylated on multiple sites. |
| Function | Transcriptional repressor. Binds specifically to GATA sequences and represses expression of GATA-regulated genes at selected sites and stages in vertebrate development. Regulates chondrocyte proliferation and differentiation. Executes multiple functions in proliferating chondrocytes, expanding the region of distal chondrocytes, activating proliferation in columnar cells and supporting the differentiation of columnar into hypertrophic chondrocytes. |
| Protein Name | Zinc Finger Transcription Factor Trps1Tricho-Rhino-Phalangeal Syndrome Type I ProteinZinc Finger Protein Gc79 |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Zinc Finger Transcription Factor Trps1 antibodyAnti-Tricho-Rhino-Phalangeal Syndrome Type I Protein antibodyAnti-Zinc Finger Protein Gc79 antibodyAnti-TRPS1 antibody |
Information sourced from Uniprot.org