Anti-TRPC5 antibody (828-878 aa) (STJ193753)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human TRPC5 at the amino acid range 828-878
General Information
| Short Description | Rabbit polyclonal anti-Short transient receptor potential channel 5 (828-878 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TRPC5 |
| Gene ID | 7224 |
| Uniprot ID | TRPC5_HUMAN |
| Immunogen | Synthesized peptide derived from the human TRPC5 at the amino acid range 828-878 |
| Immunogen Region | 828-878 aa |
| Specificity | This antibody detects endogenous levels of TRPC5 at Human/Mouse |
Additional Info
| Function | Forms a receptor-activated non-selective calcium permeant cation channel. Mediates calcium-dependent phosphatidylserine externalization and apoptosis in neurons via its association with PLSCR1. Acts on distinct neuronal populations in the hypothalamus to regulate innate behaviors including feeding, anxiety (flight/fight/fear), socialization, and maternal care. |
| Protein Name | Short Transient Receptor Potential Channel 5Trpc5Transient Receptor Protein 5Trp-5Htrp-5Htrp5 |
| Database Links | Reactome: R-HSA-3295583Reactome: R-HSA-418890 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Short Transient Receptor Potential Channel 5 antibodyAnti-Trpc5 antibodyAnti-Transient Receptor Protein 5 antibodyAnti-Trp-5 antibodyAnti-Htrp-5 antibodyAnti-Htrp5 antibodyAnti-TRPC5 antibodyAnti-TRP5 antibody |
Information sourced from Uniprot.org