Anti-TRPC5 antibody (4th Cytoplasmic Domain) (STJ13102338)
SPECIFICATIONS
ClonalityPolyclonal
HostSheep
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from 4th cytoplasmic domain of human TRPC5 (TRP5) conjugated to an immunogenic carrier protein was used as the immunogen.
General Information
| Short Description | Sheep polyclonal anti-TRPC5 (4th Cytoplasmic Domain) for use in IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Sheep |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB. A concentration of 10-50 µg/ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | TRPC5 |
| Gene ID | 7224 |
| Uniprot ID | TRPC5_HUMAN |
| Immunogen | A synthetic peptide from 4th cytoplasmic domain of human TRPC5 (TRP5) conjugated to an immunogenic carrier protein was used as the immunogen. |
| Immunogen Region | 4th Cytoplasmic Domain |
| Specificity | Specific for TRPC5. |
Additional Info
| Function | Forms a receptor-activated non-selective calcium permeant cation channel. Mediates calcium-dependent phosphatidylserine externalization and apoptosis in neurons via its association with PLSCR1. Acts on distinct neuronal populations in the hypothalamus to regulate innate behaviors including feeding, anxiety (flight/fight/fear), socialization, and maternal care. |
| Protein Name | Short Transient Receptor Potential Channel 5Trpc5Transient Receptor Protein 5Trp-5Htrp-5Htrp5 |
| Database Links | Reactome: R-HSA-3295583Reactome: R-HSA-418890 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Short Transient Receptor Potential Channel 5 antibodyAnti-Trpc5 antibodyAnti-Transient Receptor Protein 5 antibodyAnti-Trp-5 antibodyAnti-Htrp-5 antibodyAnti-Htrp5 antibodyAnti-TRPC5 antibodyAnti-TRP5 antibody |
Information sourced from Uniprot.org