| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TRPC3 |
| Gene ID: | 7222 |
| Uniprot ID: | TRPC3_HUMAN |
| Immunogen Region: | 500-600 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 500-600 of human TRPC3 (NP_001124170.1). |
| Immunogen Sequence: | FRVKTTQFTWTEMLIMVWVL GMMWSECKELWLEGPREYIL QLWNVLDFGMLSIFIAAFTA RFLAFLQATKAQQYVDSYVQ ESDLSEVTLPPEIQYFTYAR D |
| Tissue Specificity | Expressed predominantly in brain and at much lower levels in ovary, colon, small intestine, lung, prostate, placenta and testis. |
| Function | Forms a receptor-activated non-selective calcium permeant cation channel. Isoform 2: Forms a receptor-activated non-selective calcium permeant cation channel. May be operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. |
| Protein Name | Short Transient Receptor Potential Channel 3Trpc3Transient Receptor Protein 3Trp-3Htrp-3Htrp3 |
| Database Links | Reactome: R-HSA-114508Reactome: R-HSA-139853Reactome: R-HSA-3295583Reactome: R-HSA-418890Reactome: R-HSA-9022699 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Short Transient Receptor Potential Channel 3 antibodyAnti-Trpc3 antibodyAnti-Transient Receptor Protein 3 antibodyAnti-Trp-3 antibodyAnti-Htrp-3 antibodyAnti-Htrp3 antibodyAnti-TRPC3 antibodyAnti-TRP3 antibody |
Information sourced from Uniprot.org
