Anti-TRPC1 antibody (STJ191415)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-Short transient receptor potential channel 1 for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TRPC1 |
| Gene ID | 7220 |
| Uniprot ID | TRPC1_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | TRPC1 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Post Translational Modifications | Activation of PRKCA induces phosphorylation of TRPC1 and subsequent Ca2+ entry into cells. |
| Function | Forms a receptor-activated non-selective calcium permeant cation channel. Forms a heteromeric ion channel with TRPC4 or TRPC5 that has reduced calcium permeability compared to the homomeric TRPC4 or TRPC5 channel. Also permeable to monovalent ions including sodium, lithium and cesium ions. Isoform Short: Forms a receptor-activated non-selective calcium permeant cation channel. Also activated by intracellular calcium store depletion. |
| Protein Name | Short Transient Receptor Potential Channel 1Trpc1Transient Receptor Protein 1Trp-1 |
| Database Links | Reactome: R-HSA-3295583Reactome: R-HSA-418890Reactome: R-HSA-5578775Reactome: R-HSA-983695 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Short Transient Receptor Potential Channel 1 antibodyAnti-Trpc1 antibodyAnti-Transient Receptor Protein 1 antibodyAnti-Trp-1 antibodyAnti-TRPC1 antibodyAnti-TRP1 antibody |
Information sourced from Uniprot.org