Anti-TrpC1 antibody [R03-4X9] (STJA0036845)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human TRPC1
General Information
| Short Description | Rabbit monoclonal anti-TrpC1 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R03-4X9 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | TRPC1 |
| Gene ID | 7220 |
| Uniprot ID | TRPC1_HUMAN |
| Immunogen | A synthesized peptide derived from human TRPC1 |
Additional Info
| Tissue Specificity | Seems to be ubiquitous. |
| Post Translational Modifications | Activation of PRKCA induces phosphorylation of TRPC1 and subsequent Ca2+ entry into cells. |
| Function | Forms a receptor-activated non-selective calcium permeant cation channel. Forms a heteromeric ion channel with TRPC4 or TRPC5 that has reduced calcium permeability compared to the homomeric TRPC4 or TRPC5 channel. Also permeable to monovalent ions including sodium, lithium and cesium ions. Isoform Short: Forms a receptor-activated non-selective calcium permeant cation channel. Also activated by intracellular calcium store depletion. |
| Protein Name | Short Transient Receptor Potential Channel 1Trpc1Transient Receptor Protein 1Trp-1 |
| Database Links | Reactome: R-HSA-3295583Reactome: R-HSA-418890Reactome: R-HSA-5578775Reactome: R-HSA-983695 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Short Transient Receptor Potential Channel 1 antibodyAnti-Trpc1 antibodyAnti-Transient Receptor Protein 1 antibodyAnti-Trp-1 antibodyAnti-TRPC1 antibodyAnti-TRP1 antibody |
Information sourced from Uniprot.org