Anti-Troponin I1/TNNI1 antibody (1-187aa) [AT36E7] (STJA0041931)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2bk
ImmunogenRecombinant human TNNI1 (1-187aa) purified from E. coli
General Information
| Short Description | Mouse monoclonal anti-Troponin I1/TNNI1 (1-187aa) for use in ELISA and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/WB |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | AT36E7 |
| Isotype | IgG2bk |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | By protein-A affinity chromatography |
| Formulation | Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TNNI1 |
| Gene ID | 7135 |
| Uniprot ID | TNNI1_HUMAN |
| Accession Number | NP_003272 |
| Immunogen | Recombinant human TNNI1 (1-187aa) purified from E. coli |
| Immunogen Region | 1-187aa |
Additional Info
| Tissue Specificity | Highest levels observed in human skeletal muscle (e.g. gastrocnemious muscle), differentiated cultures of primary human muscle cells and rhabdomyosarcoma cells cultured in low serum medium. Expressed in C2 muscle cell myoblasts and myotubes. |
| Function | Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. |
| Protein Name | Troponin I - Slow Skeletal MuscleTroponin I - Slow-Twitch Isoform |
| Database Links | Reactome: R-HSA-390522 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Troponin I - Slow Skeletal Muscle antibodyAnti-Troponin I - Slow-Twitch Isoform antibodyAnti-TNNI1 antibody |
Information sourced from Uniprot.org