Anti-Troponin I1/TnI1 antibody (1-187) [S3MR] (STJ11103673)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal Troponin I1/TnI1 (1-187) antibody for use in WB and ELISA in human and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S3MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TNNI1 |
| Gene ID | 7135 |
| Uniprot ID | TNNI1_HUMAN |
| Immunogen Region | 1-187 |
| Immunogen Sequence | MPEVERKPKITASRKLLLKS LMLAKAKECWEQEHEEREAE KVRYLAERIPTLQTRGLSLS ALQDLCRELHAKVEVVDEER YDIEAKCLHNTREIKDLKLK VMDLRGKFKRPPLRRVRVSA DAMLRALLGSKHKVSMDLRA NLKSVKKEDTEKERPVEVGD WRKNVEAMSGMEGRKKMFDA AKSPTSQ |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-187 of human Troponin I1/TnI1 (P19237). |
Additional Info
| Tissue Specificity | Highest levels observed in human skeletal muscle (e.g. gastrocnemious muscle), differentiated cultures of primary human muscle cells and rhabdomyosarcoma cells cultured in low serum medium. Expressed in C2 muscle cell myoblasts and myotubes. |
| Function | Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. |
| Protein Name | Troponin I - Slow Skeletal MuscleTroponin I - Slow-Twitch Isoform |
| Database Links | Reactome: R-HSA-390522 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Troponin I - Slow Skeletal Muscle antibodyAnti-Troponin I - Slow-Twitch Isoform antibodyAnti-TNNI1 antibody |
Information sourced from Uniprot.org