• Western blot analysis of lysates from MCF-7 cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-TRMU antibody (368-418 aa) (STJ193991)

SKU:
STJ193991

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Mitochondrial tRNA-specific 2-thiouridylase 1 (368-418 aa) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TRMU
Gene ID: 55687
Uniprot ID: MTU1_HUMAN
Immunogen Region: 368-418 aa
Specificity: This antibody detects endogenous levels of MTU1 at Human/Mouse/Rat
Immunogen: Synthesized peptide derived from the human MTU1 at the amino acid range 368-418
Function Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base.
Protein Name Mitochondrial Trna-Specific 2-Thiouridylase 1
Mto2 Homolog
Database Links Reactome: R-HSA-6787450
Cellular Localisation Mitochondrion
Alternative Antibody Names Anti-Mitochondrial Trna-Specific 2-Thiouridylase 1 antibody
Anti-Mto2 Homolog antibody
Anti-TRMU antibody
Anti-MTU1 antibody
Anti-TRMT1 antibody

Information sourced from Uniprot.org

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