Anti-TRMT6 antibody (175-225 aa) (STJ195314)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human TRM6 at the amino acid range 175-225
General Information
| Short Description | Rabbit polyclonal anti-tRNA-N1-methyltransferase non-catalytic subunit TRM6-methyltransferase non-catalytic subunit TRM6-methyltransferase subunit TRM6MTase subunit TRM6 (175-225 aa) for use in WB in Human and Mouse samples. Datasheet included with d |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TRMT6 |
| Gene ID | 51605 |
| Uniprot ID | TRM6_HUMAN |
| Immunogen | Synthesized peptide derived from the human TRM6 at the amino acid range 175-225 |
| Immunogen Region | 175-225 aa |
| Specificity | This antibody detects endogenous levels of TRM6 at Human/Mouse |
Additional Info
| Function | Substrate-binding subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. Together with the TRMT61A catalytic subunit, part of a mRNA N(1)-methyltransferase complex that mediates methylation of adenosine residues at the N(1) position of a small subset of mRNAs: N(1) methylation takes place in tRNA T-loop-like structures of mRNAs and is only present at low stoichiometries. |
| Protein Name | TrnaAdenine(58-N(1-Methyltransferase Non-Catalytic Subunit Trm6Mrna Methyladenosine-N(1-Methyltransferase Non-Catalytic Subunit Trm6Trna(M1a58-Methyltransferase Subunit Trm6Trna(M1a58mtase Subunit Trm6 |
| Database Links | Reactome: R-HSA-6782315 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Trna antibodyAnti-Adenine(58-N(1-Methyltransferase Non-Catalytic Subunit Trm6 antibodyAnti-Mrna Methyladenosine-N(1-Methyltransferase Non-Catalytic Subunit Trm6 antibodyAnti-Trna(M1a58-Methyltransferase Subunit Trm6 antibodyAnti-Trna(M1a58mtase Subunit Trm6 antibodyAnti-TRMT6 antibodyAnti-KIAA1153 antibodyAnti-TRM6 antibodyAnti-CGI-09 antibody |
Information sourced from Uniprot.org