Anti-TRIP6 antibody (221-270 aa) (STJ192559)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 221-270
General Information
| Short Description | Rabbit polyclonal anti-Thyroid receptor-interacting protein 6 (221-270 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TRIP6 |
| Gene ID | 7205 |
| Uniprot ID | TRIP6_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 221-270 |
| Immunogen Region | 221-270 aa |
| Specificity | TRIP6 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Post Translational Modifications | Phosphorylation at Tyr-55 by SRC is required for enhancement of lysophosphatidic acid-induced cell migration. Tyr-55 is dephosphorylated by PTPN13. |
| Function | Relays signals from the cell surface to the nucleus to weaken adherens junction and promote actin cytoskeleton reorganization and cell invasiveness. Involved in lysophosphatidic acid-induced cell adhesion and migration. Acts as a transcriptional coactivator for NF-kappa-B and JUN, and mediates the transrepression of these transcription factors induced by glucocorticoid receptor. |
| Protein Name | Thyroid Receptor-Interacting Protein 6Tr-Interacting Protein 6Trip-6Opa-Interacting Protein 1Oip-1Zyxin-Related Protein 1Zrp-1 |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonCell JunctionFocal AdhesionNucleusShuttles Between Nucleus And CytoplasmColocalizes With Actin |
| Alternative Antibody Names | Anti-Thyroid Receptor-Interacting Protein 6 antibodyAnti-Tr-Interacting Protein 6 antibodyAnti-Trip-6 antibodyAnti-Opa-Interacting Protein 1 antibodyAnti-Oip-1 antibodyAnti-Zyxin-Related Protein 1 antibodyAnti-Zrp-1 antibodyAnti-TRIP6 antibodyAnti-OIP1 antibody |
Information sourced from Uniprot.org