| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Thyroid receptor-interacting protein 6 (221-270 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TRIP6 |
| Gene ID: |
7205 |
| Uniprot ID: |
TRIP6_HUMAN |
| Immunogen Region: |
221-270 aa |
| Specificity: |
TRIP6 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: |
Synthesized peptide derived from the human protein at the amino acid range 221-270 |
| Post Translational Modifications | Phosphorylation at Tyr-55 by SRC is required for enhancement of lysophosphatidic acid-induced cell migration. Tyr-55 is dephosphorylated by PTPN13. |
| Function | Relays signals from the cell surface to the nucleus to weaken adherens junction and promote actin cytoskeleton reorganization and cell invasiveness. Involved in lysophosphatidic acid-induced cell adhesion and migration. Acts as a transcriptional coactivator for NF-kappa-B and JUN, and mediates the transrepression of these transcription factors induced by glucocorticoid receptor. |
| Protein Name | Thyroid Receptor-Interacting Protein 6Tr-Interacting Protein 6Trip-6Opa-Interacting Protein 1Oip-1Zyxin-Related Protein 1Zrp-1 |
| Cellular Localisation | CytoplasmCytoskeletonCell JunctionFocal AdhesionNucleusShuttles Between Nucleus And CytoplasmColocalizes With Actin |
| Alternative Antibody Names | Anti-Thyroid Receptor-Interacting Protein 6 antibodyAnti-Tr-Interacting Protein 6 antibodyAnti-Trip-6 antibodyAnti-Opa-Interacting Protein 1 antibodyAnti-Oip-1 antibodyAnti-Zyxin-Related Protein 1 antibodyAnti-Zrp-1 antibodyAnti-TRIP6 antibodyAnti-OIP1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
