Anti-TRIM9 antibody (Internal Region) (STJ13102488)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from internal region of mouse TRIM9 conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in human and rat.
General Information
| Short Description | Rabbit polyclonal anti-TRIM9 (Internal Region) for use in IHC and WB in Mouse, Rat and Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Mouse/Rat/Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB. A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | Trim9 |
| Gene ID | 94090 |
| Uniprot ID | TRIM9_MOUSE |
| Immunogen | A synthetic peptide from internal region of mouse TRIM9 conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in human and rat. |
| Immunogen Region | Internal Region |
| Specificity | Specific for TRIM9. |
Additional Info
| Post Translational Modifications | Auto-ubiquitinated. |
| Function | E3 ubiquitin-protein ligase which ubiquitinates itself in cooperation with an E2 enzyme UBE2D2/UBC4 and serves as a targeting signal for proteasomal degradation. May play a role in regulation of neuronal functions. May act as a regulator of synaptic vesicle exocytosis by controlling the availability of SNAP25 for the SNARE complex formation. |
| Protein Name | E3 Ubiquitin-Protein Ligase Trim9Ring-Type E3 Ubiquitin Transferase Trim9Tripartite Motif-Containing Protein 9 |
| Database Links | Reactome: R-MMU-983168 |
| Cellular Localisation | CytoplasmCell ProjectionDendriteCytoplasmic VesicleSecretory VesicleSynaptic VesicleSynapseCytoskeletonEnriched At Synaptic Terminals Where It Exists In A Soluble Form And A Synaptic Vesicle-Associated FormAssociated With The CytoskeletonFound In Proximal Dendrites Of Pyramidal Neurons In The Cerebral Cortex And HippocampusAnd Purkinje Cells In The Cerebellum |
| Alternative Antibody Names | Anti-E3 Ubiquitin-Protein Ligase Trim9 antibodyAnti-Ring-Type E3 Ubiquitin Transferase Trim9 antibodyAnti-Tripartite Motif-Containing Protein 9 antibodyAnti-Trim9 antibodyAnti-Kiaa0282 antibody |
Information sourced from Uniprot.org