Anti-TRIM66 antibody (750-970) (STJ11100365)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal TRIM66 (750-970) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TRIM66 |
| Gene ID | 9866 |
| Uniprot ID | TRI66_HUMAN |
| Immunogen Region | 750-970 |
| Immunogen Sequence | LATCPLQSIPPVSDMQPETG SSSSSGRTSGSLCPRDGADP SLENALCKVKLEEPINLSVK KPPLAPVVSTSTALQQYQNP KECENFEQGALELDAKENQS IRAFNSEHKIPYVRLERLKI CAASSGEMPVFKLKPQKNDQ DGSFLLIIECGTESSSMSIK VSQDRLSEATQAPGLEGRKV TVTSLAGQRPPEVEGTSPEE HRLIPRTPGAKKGPPAPIEN E |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 750-970 of human TRIM66 (NP_055633.1). |
Additional Info
| Function | May function as transcription repressor.The repressive effects are mediated, at least in part, by recruitment of deacetylase activity. May play a role as negative regulator of postmeiotic genes acting through CBX3 complex formation and centromere association. |
| Protein Name | Tripartite Motif-Containing Protein 66 |
| Database Links | |
| Cellular Localisation | NucleusForms Discrete Foci Within The Centromeric Chromocenter And Surrounding Nucleoplasm |
| Alternative Antibody Names | Anti-Tripartite Motif-Containing Protein 66 antibodyAnti-TRIM66 antibodyAnti-C11orf29 antibodyAnti-KIAA0298 antibody |
Information sourced from Uniprot.org