Anti-TRIM47 antibody (356-530) (STJ119831)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
STJ119831
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General Information

Short DescriptionRabbit polyclonal TRIM47 (356-530) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/IF/ICC/ELISA
HostRabbit
ReactivityHuman/Mouse/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
ConcentrationLot specific
PurificationAffinity purification
Dilution RangeWB:1:100-1:500
IF/ICC:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
FormulationPBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Storage InstructionStore at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolTRIM47
Gene ID91107
Uniprot IDTRI47_HUMAN
Immunogen Region356-530
Immunogen SequenceELSFTKSSQAVRAVRDMLAV ACVNQWEQLRGPGGNEDGPQ KLDSEADAEPQDLESTNLLE SEAPRDYFLKFAYIVDLDSD TADKFLQLFGTKGVKRVLCP INYPLSPTRFTHCEQVLGEG ALDRGTYYWEVEIIEGWVSM GVMAEDFSPQEPYDRGRLGR NAHSCCLQWNGRSFS
SpecificityRecombinant fusion protein containing a sequence corresponding to amino acids 356-530 of human TRIM47 (NP_258411.2).

Additional Info

Tissue Specificity Low expression in most tissues. Higher expression in kidney tubular cells. Overexpressed in astrocytoma tumor cells.
Function E3 ubiquitin-protein ligase that mediates the ubiquitination and proteasomal degradation of CYLD.
Protein Name E3 Ubiquitin-Protein Ligase Trim47
Gene Overexpressed In Astrocytoma Protein
Ring Finger Protein 100
Tripartite Motif-Containing Protein 47
Database Links
Cellular Localisation Cytoplasm
Nucleus
Alternative Antibody Names Anti-E3 Ubiquitin-Protein Ligase Trim47 antibody
Anti-Gene Overexpressed In Astrocytoma Protein antibody
Anti-Ring Finger Protein 100 antibody
Anti-Tripartite Motif-Containing Protein 47 antibody
Anti-TRIM47 antibody
Anti-GOA antibody
Anti-RNF100 antibody

Information sourced from Uniprot.org

Citations

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