Anti-TRIM47 antibody (356-530) (STJ119831)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal TRIM47 (356-530) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:100-1:500IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TRIM47 |
| Gene ID | 91107 |
| Uniprot ID | TRI47_HUMAN |
| Immunogen Region | 356-530 |
| Immunogen Sequence | ELSFTKSSQAVRAVRDMLAV ACVNQWEQLRGPGGNEDGPQ KLDSEADAEPQDLESTNLLE SEAPRDYFLKFAYIVDLDSD TADKFLQLFGTKGVKRVLCP INYPLSPTRFTHCEQVLGEG ALDRGTYYWEVEIIEGWVSM GVMAEDFSPQEPYDRGRLGR NAHSCCLQWNGRSFS |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 356-530 of human TRIM47 (NP_258411.2). |
Additional Info
| Tissue Specificity | Low expression in most tissues. Higher expression in kidney tubular cells. Overexpressed in astrocytoma tumor cells. |
| Function | E3 ubiquitin-protein ligase that mediates the ubiquitination and proteasomal degradation of CYLD. |
| Protein Name | E3 Ubiquitin-Protein Ligase Trim47Gene Overexpressed In Astrocytoma ProteinRing Finger Protein 100Tripartite Motif-Containing Protein 47 |
| Database Links | |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-E3 Ubiquitin-Protein Ligase Trim47 antibodyAnti-Gene Overexpressed In Astrocytoma Protein antibodyAnti-Ring Finger Protein 100 antibodyAnti-Tripartite Motif-Containing Protein 47 antibodyAnti-TRIM47 antibodyAnti-GOA antibodyAnti-RNF100 antibody |
Information sourced from Uniprot.org