• Western blot analysis of the lysates from Jurkat cells using TRIM3 antibody.
  • Western blot analysis of lysates from COLO cells, using TRIM3 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Immunofluorescence analysis of NIH/3T3 cells, using TRIM3 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Immunohistochemistry analysis of paraffin-embedded human brain tissue, using TRIM3 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of COLO cells using TRIM3 Polyclonal Antibody. Secondary antibody was diluted at 1:20000

Anti-TRIM3 antibody (1-50 aa) (STJ96101)

SKU:
STJ96101

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Tripartite motif-containing protein 3 (1-50 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:40000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TRIM3
Gene ID: 10612
Uniprot ID: TRIM3_HUMAN
Immunogen Region: 1-50 aa
Specificity: TRIM3 Polyclonal Antibody detects endogenous levels of TRIM3 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human TRIM3 at the amino acid range 1-50
Function E3 ubiquitin ligase that plays essential roles in neuronal functions such as regulation of neuronal plasticity, learning, and memory. In addition to its neuronal functions, participates in other biological processes such as innate immunity or cell cycle regulation. Component of the cytoskeleton-associated recycling or transport complex in neurons, polyubiquitinates gamma-actin, thus regulating neuronal plasticity, learning, and memory. Ubiquitinates postsynaptic scaffold GKAP, a neuronal substrate involved in synaptic remodeling and thereby modulates dendritic spine morphology. Positively regulates motility of microtubule-dependent motor protein KIF21B. Induces growth arrest via its RING-dependent E3 ligase activity and ubiquinates CDKN1A. Positively regulates TLR3-mediated signaling by mediating 'Lys-63'-linked polyubiquitination of TLR3. In turn, promotes the recognition and sorting of polyubiquitinated TLR3 by the ESCRT complexes.
Protein Name Tripartite Motif-Containing Protein 3
Brain-Expressed Ring Finger Protein
Ring Finger Protein 22
Ring Finger Protein 97
Database Links Reactome: R-HSA-877300
Cellular Localisation Cytoplasm
Early Endosome
Golgi Apparatus
Trans-Golgi Network
Cell Projection
Dendrite
Mainly Located In The Golgi Apparatus And Transported To The Early Endosomes Upon Stimulation With Dsrna
Alternative Antibody Names Anti-Tripartite Motif-Containing Protein 3 antibody
Anti-Brain-Expressed Ring Finger Protein antibody
Anti-Ring Finger Protein 22 antibody
Anti-Ring Finger Protein 97 antibody
Anti-TRIM3 antibody
Anti-BERP antibody
Anti-RNF22 antibody
Anti-RNF97 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance