| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Tripartite motif-containing protein 2 (162-212 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TRIM2 |
| Gene ID: |
23321 |
| Uniprot ID: |
TRIM2_HUMAN |
| Immunogen Region: |
162-212 aa |
| Specificity: |
This antibody detects endogenous levels of TRIM2 at Human/Mouse/Rat |
| Immunogen: |
Synthesized peptide derived from the human TRIM2 at the amino acid range 162-212 |
| Function | UBE2D1-dependent E3 ubiquitin-protein ligase that mediates the ubiquitination of NEFL and of phosphorylated BCL2L11. Plays a neuroprotective function. May play a role in neuronal rapid ischemic tolerance. Plays a role in antiviral immunity and limits New World arenavirus infection independently of its ubiquitin ligase activity. |
| Protein Name | Tripartite Motif-Containing Protein 2E3 Ubiquitin-Protein Ligase Trim2Ring Finger Protein 86Ring-Type E3 Ubiquitin Transferase Trim2 |
| Database Links | Reactome: R-HSA-877300 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Tripartite Motif-Containing Protein 2 antibodyAnti-E3 Ubiquitin-Protein Ligase Trim2 antibodyAnti-Ring Finger Protein 86 antibodyAnti-Ring-Type E3 Ubiquitin Transferase Trim2 antibodyAnti-TRIM2 antibodyAnti-KIAA0517 antibodyAnti-RNF86 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
