Anti-TRIM2 antibody (162-212 aa) (STJ193894)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human TRIM2 at the amino acid range 162-212
General Information
| Short Description | Rabbit polyclonal anti-Tripartite motif-containing protein 2 (162-212 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TRIM2 |
| Gene ID | 23321 |
| Uniprot ID | TRIM2_HUMAN |
| Immunogen | Synthesized peptide derived from the human TRIM2 at the amino acid range 162-212 |
| Immunogen Region | 162-212 aa |
| Specificity | This antibody detects endogenous levels of TRIM2 at Human/Mouse/Rat |
Additional Info
| Function | UBE2D1-dependent E3 ubiquitin-protein ligase that mediates the ubiquitination of NEFL and of phosphorylated BCL2L11. Plays a neuroprotective function. May play a role in neuronal rapid ischemic tolerance. Plays a role in antiviral immunity and limits New World arenavirus infection independently of its ubiquitin ligase activity. |
| Protein Name | Tripartite Motif-Containing Protein 2E3 Ubiquitin-Protein Ligase Trim2Ring Finger Protein 86Ring-Type E3 Ubiquitin Transferase Trim2 |
| Database Links | Reactome: R-HSA-877300 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Tripartite Motif-Containing Protein 2 antibodyAnti-E3 Ubiquitin-Protein Ligase Trim2 antibodyAnti-Ring Finger Protein 86 antibodyAnti-Ring-Type E3 Ubiquitin Transferase Trim2 antibodyAnti-TRIM2 antibodyAnti-KIAA0517 antibodyAnti-RNF86 antibody |
Information sourced from Uniprot.org