| Host: | Mouse |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-Tri-Methyl-Histone H3.1 and Histone H3.2 and Histone H3.3-Lys79 is suitable for use in Western Blot research applications. |
| Clonality : | Monoclonal |
| Clone ID : | 2C3 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Formulation: | Liquid in PBS pH7.4, 0.5% BSA, 0.02% Sodium Azide and 50% Glycerol. |
| Purification: | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Dilution Range: | WB 1:1000-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | H3-3A.H3-3B H3C1.H3C2.H |
| Gene ID: | 3020/3021 8350/8351/8352/8353/8354/8355/8356/8357/8358/8968 |
| Uniprot ID: | H33_HUMAN H31_HUMAN H32_HUMAN < |
| Specificity: | The antibody detects endogenous Histone H3 (tri methyl K9) protein. |
| Immunogen: | Synthetic Peptide of Histone H3 (Tri Methyl Lys9) |
| Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
| Protein Name | Histone H3.1 Histone H3/A Histone H3/B Histone H3/C Histone H3/D Histone H3/F Histone H3/H Histone H3/I Histone H3/J Histone H3/K Histone H3/L |
| Database Links | Reactome: R-HSA-1266695 Reactome: R-HSA-1912408 Reactome: R-HSA-201722 Reactome: R-HSA-212300 Reactome: R-HSA-2299718 Reactome: R-HSA-2559580 Reactome: R-HSA-2559582 Reactome: R-HSA-3214815 Reactome: R-HSA-3214841 Reactome: R-HSA-3214842 Reactome: R-HSA-3214847 Reactome: R-HSA-3214858 Reactome: R-HSA-3247509 Reactome: R-HSA-427359 Reactome: R-HSA-427389 Reactome: R-HSA-427413 Reactome: R-HSA-5250924 Reactome: R-HSA-5334118 Reactome: R-HSA-5578749 Reactome: R-HSA-5617472 Reactome: R-HSA-5625886 Reactome: R-HSA-73728 Reactome: R-HSA-73772 Reactome: R-HSA-8936459 Reactome: R-HSA-8939236 Reactome: R-HSA-9018519 Reactome: R-HSA-912446 Reactome: R-HSA-9609690 Reactome: R-HSA-9610379 Reactome: R-HSA-9616222 Reactome: R-HSA-977225 Reactome: R-HSA-983231 |
| Cellular Localisation | Nucleus Chromosome |
| Alternative Antibody Names | Anti-Histone H3.1 antibody Anti-Histone H3/A antibody Anti-Histone H3/B antibody Anti-Histone H3/C antibody Anti-Histone H3/D antibody Anti-Histone H3/F antibody Anti-Histone H3/H antibody Anti-Histone H3/I antibody Anti-Histone H3/J antibody Anti-Histone H3/K antibody Anti-Histone H3/L antibody Anti-H3C1 antibody Anti-H3FA antibody Anti-HIST1H3A.H3C2 antibody Anti-H3FL antibody Anti-HIST1H3B.H3C3 antibody Anti-H3FC antibody Anti-HIST1H3C.H3C4 antibody Anti-H3FB antibody Anti-HIST1H3D.H3C6 antibody Anti-H3FD antibody Anti-HIST1H3E.H3C7 antibody Anti-H3FI antibody Anti-HIST1H3F.H3C8 antibody Anti-H3FH antibody Anti-HIST1H3G.H3C10 antibody Anti-H3FK antibody Anti-HIST1H3H.H3C11 antibody Anti-H3FF antibody Anti-HIST1H3I.H3C12 antibody Anti-H3FJ antibody Anti-HIST1H3J antibody |
Information sourced from Uniprot.org