Anti-Transferrin antibody [1G7-8D7-4F9] (STJA0032977)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenPurified recombinant protein expressed in E.coli.
General Information
| Short Description | Mouse monoclonal anti-Transferrin for use in WB, IHC-P and ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 1G7-8D7-4F9 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100ELISA 1:10000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | TF |
| Gene ID | 7018 |
| Uniprot ID | TRFE_HUMAN |
| Immunogen | Purified recombinant protein expressed in E.coli. |
Additional Info
| Tissue Specificity | Expressed by the liver and secreted in plasma. |
| Function | Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. (Microbial infection) Serves as an iron source for Neisseria species, which capture the protein and extract its iron for their own use. (Microbial infection) Serves as an iron source for parasite T.brucei (strain 427), which capture TF via its own transferrin receptor ESAG6:ESAG7 and extract its iron for its own use. |
| Protein Name | SerotransferrinTransferrinBeta-1 Metal-Binding GlobulinSiderophilin |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-381426Reactome: R-HSA-8856825Reactome: R-HSA-8856828Reactome: R-HSA-8957275Reactome: R-HSA-917937Reactome: R-HSA-917977 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Serotransferrin antibodyAnti-Transferrin antibodyAnti-Beta-1 Metal-Binding Globulin antibodyAnti-Siderophilin antibodyAnti-TF antibodyAnti-PRO1400 antibody |
Information sourced from Uniprot.org