Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-TRAFD1 (1-260) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:1000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
TRAFD1 |
Gene ID: |
10906 |
Uniprot ID: |
TRAD1_HUMAN |
Immunogen Region: |
1-260 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human TRAFD1 (NP_006691.1). |
Immunogen Sequence: |
MAEFLDDQETRLCDNCKKEI PVFNFTIHEIHCQRNIGMCP TCKEPFPKSDMETHMAAEHC QVTCKCNKKLEKRLLKKHEE TECPLRLAVCQHCDLELSIL KLKEHEDYCGARTELCGNCG RNVLVKDLKTHPEVCGREGE EKRNEVAIPPNAYDESWGQD GIWIASQLLRQIEALDPPMR LPRRPLRAFESDVFHNRTTN QRNITAQVSIQNNLFEEQER QERNRGQQPPKEGGEESAN |
Function | Negative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation. May negatively regulate the RLH pathway downstream from MAVS and upstream of NF-kappa-B and IRF3. |
Protein Name | Traf-Type Zinc Finger Domain-Containing Protein 1Protein Fln29 |
Alternative Antibody Names | Anti-Traf-Type Zinc Finger Domain-Containing Protein 1 antibodyAnti-Protein Fln29 antibodyAnti-TRAFD1 antibodyAnti-FLN29 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance