Anti-TRAF3IP1 antibody (Internal) (STJ71566)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-TRAF3IP1 (Internal) is suitable for use in ELISA research applications. |
| Applications | Pep-ELISA |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Preliminary experiments in Human Bone Marrow, Heart, Testis and Thyroid Gland lysates gave no specific signal but low background (at antibody concentration up to 1µg/ml). We would appr |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | TRAF3IP1 |
| Gene ID | 26146 |
| Uniprot ID | MIPT3_HUMAN |
| Accession Number | NP_056465.2 |
| Immunogen Region | Internal |
| Immunogen Sequence | RCENIQPNPTEKQK |
Additional Info
| Function | Plays an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules. Involved in kidney development and epithelial morphogenesis. Involved in the regulation of microtubule cytoskeleton organization. Is a negative regulator of microtubule stability, acting through the control of MAP4 levels. Involved in ciliogenesis. |
| Protein Name | Traf3-Interacting Protein 1Interleukin-13 Receptor Alpha 1-Binding Protein 1Intraflagellar Transport Protein 54 HomologMicrotubule-Interacting Protein Associated With Traf3Mip-T3 |
| Database Links | Reactome: R-HSA-5620924 |
| Cellular Localisation | CytoplasmCytoskeletonCell ProjectionCiliumCilium AxonemeCilium Basal BodyMicrotubulesIn The CiliumIt Is Observed At The Ciliary BaseCiliary Transition Zone And Ciliary Tip |
| Alternative Antibody Names | Anti-Traf3-Interacting Protein 1 antibodyAnti-Interleukin-13 Receptor Alpha 1-Binding Protein 1 antibodyAnti-Intraflagellar Transport Protein 54 Homolog antibodyAnti-Microtubule-Interacting Protein Associated With Traf3 antibodyAnti-Mip-T3 antibodyAnti-TRAF3IP1 antibodyAnti-IFT54 antibodyAnti-MIPT3 antibody |
Information sourced from Uniprot.org