Anti-TPM3 antibody (1-284) (STJ115518)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
STJ115518
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General Information

Short DescriptionRabbit polyclonal TPM3 (1-284) antibody for use in WB and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/ELISA
HostRabbit
ReactivityMouse
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
ConcentrationLot specific
PurificationAffinity purification
Dilution RangeWB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
FormulationPBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage InstructionStore at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolTPM3
Gene ID7170
Uniprot IDTPM3_HUMAN
Immunogen Region1-284
Immunogen SequenceMMEAIKKKMQMLKLDKENAL DRAEQAEAEQKQAEERSKQL EDELAAMQKKLKGTEDELDK YSEALKDAQEKLELAEKKAA DAEAEVASLNRRIQLVEEEL DRAQERLATALQKLEEAEKA ADESERGMKVIENRALKDEE KMELQEIQLKEAKHIAEEAD RKYEEVARKLVIIEGDLERT EERAELAESKCSELEEELKN VTNNLKSLEAQAEKYSQKED KYEEEIKILTDKLKEAETR
SpecificityRecombinant fusion protein containing a sequence corresponding to amino acids 1-284 of human TPM3 (NP_689476.2).

Additional Info

Function Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
Protein Name Tropomyosin Alpha-3 Chain
Gamma-Tropomyosin
Tropomyosin-3
Tropomyosin-5
Htm5
Database Links Reactome: R-HSA-390522
Reactome: R-HSA-445355
Reactome: R-HSA-9013424
Reactome: R-HSA-9725370
Cellular Localisation Cytoplasm
Cytoskeleton
Alternative Antibody Names Anti-Tropomyosin Alpha-3 Chain antibody
Anti-Gamma-Tropomyosin antibody
Anti-Tropomyosin-3 antibody
Anti-Tropomyosin-5 antibody
Anti-Htm5 antibody
Anti-TPM3 antibody

Information sourced from Uniprot.org

Citations

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