Anti-TPK1 antibody (171-221) (STJA0006593)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human TPK1 AA range: 171-221
General Information
| Short Description | Rabbit polyclonal anti-Thiamin pyrophosphokinase 1 (171-221) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TPK1 |
| Gene ID | 27010 |
| Uniprot ID | TPK1_HUMAN |
| Immunogen | Synthesized peptide derived from human TPK1 AA range: 171-221 |
| Immunogen Region | 171-221 |
| Specificity | This antibody detects endogenous levels of human TPK1 |
Additional Info
| Function | Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate (TPP) utilizing UTP and therefore links the biosynthesis of TPP to pyrimidines metabolism. By producing thiamine pyrophosphate, a cofactor of the mitochondrial pyruvate dehydrogenase indirectly regulates pyruvate oxidation and lipogenesis. Although it can also catalyze thiamine phosphorylation using ATP and CTP in vitro, it does so with significantly lower efficiency and without physiological relevance evidence. |
| Protein Name | Thiamine Pyrophosphokinase 1Htpk1Placental Protein 20Pp20Thiamin Pyrophosphokinase 1 |
| Database Links | Reactome: R-HSA-196819 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Thiamine Pyrophosphokinase 1 antibodyAnti-Htpk1 antibodyAnti-Placental Protein 20 antibodyAnti-Pp20 antibodyAnti-Thiamin Pyrophosphokinase 1 antibodyAnti-TPK1 antibody |
Information sourced from Uniprot.org