Anti-TPI1 antibody (1-249) (STJ118179)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal TPI1 (1-249) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:100-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TPI1 |
| Gene ID | 7167 |
| Uniprot ID | TPIS_HUMAN |
| Immunogen Region | 1-249 |
| Immunogen Sequence | MAPSRKFFVGGNWKMNGRKQ SLGELIGTLNAAKVPADTEV VCAPPTAYIDFARQKLDPKI AVAAQNCYKVTNGAFTGEIS PGMIKDCGATWVVLGHSERR HVFGESDELIGQKVAHALAE GLGVIACIGEKLDEREAGIT EKVVFEQTKVIADNVKDWSK VVLAYEPVWAIGTGKTATPQ QAQEVHEKLRGWLKSNVSDA VAQSTRIIYGGSVTGATCKE LASQPDVDGFLVGGASLKP |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-249 of human TPI1 (NP_000356.1). |
Additional Info
| Function | Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis. It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids. |
| Protein Name | Triosephosphate IsomeraseTimMethylglyoxal SynthaseTriose-Phosphate Isomerase |
| Database Links | Reactome: R-HSA-70171Reactome: R-HSA-70263 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Triosephosphate Isomerase antibodyAnti-Tim antibodyAnti-Methylglyoxal Synthase antibodyAnti-Triose-Phosphate Isomerase antibodyAnti-TPI1 antibodyAnti-TPI antibody |
Information sourced from Uniprot.org