• Western blot analysis of lysates from Jurkat cells, using Tryptophan Hydroxylase Antibody. The lane on the right is blocked with the synthesized peptide.
  • Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Tryptophan Hydroxylase Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of HepG2 cells using TPH1 Polyclonal Antibody diluted at 1：500. Secondary antibody was diluted at 1:20000
  • Immunofluorescence analysis of HUVEC cells, using Tryptophan Hydroxylase Antibody. The picture on the right is blocked with the synthesized peptide.
  • Immunofluorescence analysis of Hela cell. 1, TPH1 Polyclonal Antibody (green) was diluted at 1:200 (4°C overnight). 2, Goat Anti Rabbit Alexa Fluor 488 Catalog: (NA was diluted at 1:1000 (room temperature, 50min). 3 DAPI (blue) 10min.

Anti-TPH1 antibody (231-280 aa) (STJ96075)

SKU:
STJ96075

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Tryptophan 5-hydroxylase 1 (231-280 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TPH1
Gene ID: 7166
Uniprot ID: TPH1_HUMAN
Immunogen Region: 231-280 aa
Specificity: TPH1 Polyclonal Antibody detects endogenous levels of TPH1 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human Tryptophan Hydroxylase at the amino acid range 231-280
Post Translational Modifications Ubiquitinated, leading to its degradation by the proteasome. Ubiquitinated is triggered by phosphorylation. Phosphorylated.triggering degradation by the proteasome.
Function Oxidizes L-tryptophan to 5-hydroxy-l-tryptophan in the rate-determining step of serotonin biosynthesis.
Protein Name Tryptophan 5-Hydroxylase 1
Tryptophan 5-Monooxygenase 1
Database Links Reactome: R-HSA-209931
Reactome: R-HSA-9031628
Alternative Antibody Names Anti-Tryptophan 5-Hydroxylase 1 antibody
Anti-Tryptophan 5-Monooxygenase 1 antibody
Anti-TPH1 antibody
Anti-TPH antibody
Anti-TPRH antibody
Anti-TRPH antibody

Information sourced from Uniprot.org

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