Anti-TP53-R175H Mutant antibody (STJA0033674)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2b
ImmunogenA synthetic peptide from the internal region of TP53 which includes the mutation of R175H, human origin
General Information
| Short Description | Mouse monoclonal anti-TP53-R175H Mutant for use in WB, IHC-P, ICC, IF and ELISA in Vertebrates samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ICC/IF/ELISA |
| Host | Mouse |
| Reactivity | Vertebrates |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Isotype | IgG2b |
| Conjugation | Unconjugated |
| Purification | Purified from ascites |
| Dilution Range | WB-1:1000-1:5000IHC-P-1:50-1:100ELISA-1:1000-1:5000IF-1:50-1:200 |
| Formulation | Liquid in PBS (without Mg2+ and Ca2+) , pH 7.4, 150 mM NaCl, 50% glycerol |
| Storage Instruction | Store at-20°C. Avoid freeze/thaw cycles. |
Target Information
| Immunogen | A synthetic peptide from the internal region of TP53 which includes the mutation of R175H, human origin |
Additional Info
| Background | TP53 belongs to the p53 proteins family. It is ubiquitously expressed, acts as a tumor suppressor in many tumor types and induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Defects in TP53 are a cause of esophageal cancer (ESCR) , lung cancer (LNCR) , adrenocortical carcinoma (ADCC) , choroid plexus papilloma (CPLPA) and so on. |
Information sourced from Uniprot.org