Anti-TOMM20 antibody [R03-7F6] (STJA0034939)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant protein of human TOMM20
General Information
| Short Description | Rabbit monoclonal anti-TOMM20 for use in WB, IHC-F, IHC-P, ICC and IF in Human and Hamster samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-F/IHC-P/ICC/IF |
| Host | Rabbit |
| Reactivity | Human/Hamster |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R03-7F6 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100IF 1:50-1:200 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | TOMM20 |
| Gene ID | 9804 |
| Uniprot ID | TOM20_HUMAN |
| Immunogen | Recombinant protein of human TOMM20 |
Additional Info
| Post Translational Modifications | Ubiquitinated by PRKN during mitophagy, leading to its degradation and enhancement of mitophagy. Deubiquitinated by USP30. |
| Function | Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with TOM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the TOM40 translocation pore. Required for the translocation across the mitochondrial outer membrane of cytochrome P450 monooxygenases. |
| Protein Name | Mitochondrial Import Receptor Subunit Tom20 HomologMitochondrial 20 Kda Outer Membrane ProteinOuter Mitochondrial Membrane Receptor Tom20 |
| Database Links | Reactome: R-HSA-1268020Reactome: R-HSA-5205685Reactome: R-HSA-5689880 |
| Cellular Localisation | Mitochondrion Outer MembraneSingle-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Mitochondrial Import Receptor Subunit Tom20 Homolog antibodyAnti-Mitochondrial 20 Kda Outer Membrane Protein antibodyAnti-Outer Mitochondrial Membrane Receptor Tom20 antibodyAnti-TOMM20 antibodyAnti-KIAA0016 antibody |
Information sourced from Uniprot.org