| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 IHC-P:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TNKS1BP1 |
| Gene ID: | 85456 |
| Uniprot ID: | TB182_HUMAN |
| Immunogen Region: | 700-1000 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 700-1000 of human TNKS1BP1 (NP_203754.2). |
| Immunogen Sequence: | RRGAGAELKDTQSPSTCSEG LLGWSQKDLQSEFGITGDPQ PSSFSPSSWCQGASQDYGLG GASPRGDPGLGERDWTSKYG QGAGEGSTREWASRCGIGQE EMEASSSQDQSKVSAPGVLT AQDRVVGKPAQLGTQRSQEA DVQDWEFRKRDSQGTYSSRD AELQDQEFGKRDSLGTYSSR DVSLGDWEFGKRDSLGAYAS QDANEQGQDLGKRDHHGRYS SQDADEQDWEFQKRDVSLG |
| Tissue Specificity | Detected in testis, ovary, lung, skeletal muscle, heart, prostate and pancreas, and at very low levels in brain and peripheral blood leukocytes. |
| Post Translational Modifications | ADP-ribosylated by TNKS1 (in vitro). |
| Protein Name | 182 Kda Tankyrase-1-Binding Protein |
| Database Links | Reactome: R-HSA-429947 Reactome: R-HSA-6804115 Reactome: R-HSA-9820841 |
| Cellular Localisation | Nucleus Cytoplasm Cytoskeleton Chromosome Colocalizes With Chromosomes During Mitosis And In The Cytoplasm With Cortical Actin |
| Alternative Antibody Names | Anti-182 Kda Tankyrase-1-Binding Protein antibody Anti-TNKS1BP1 antibody Anti-KIAA1741 antibody Anti-TAB182 antibody |
Information sourced from Uniprot.org