Anti-TNFSF18 antibody (101-150 aa) (STJ191827)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein at the amino acid range 101-150
General Information
| Short Description | Rabbit polyclonal anti-Tumor necrosis factor ligand superfamily member 18 (101-150 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TNFSF18 |
| Gene ID | 8995 |
| Uniprot ID | TNF18_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein at the amino acid range 101-150 |
| Immunogen Region | 101-150 aa |
| Specificity | TNF18 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B. Triggers increased phosphorylation of STAT1 and up-regulates expression of VCAM1 and ICAM1. Promotes leukocyte adhesion to endothelial cells. Regulates migration of monocytes from the splenic reservoir to sites of inflammation. |
| Protein Name | Tumor Necrosis Factor Ligand Superfamily Member 18Activation-Inducible Tnf-Related LigandAitrlGlucocorticoid-Induced Tnf-Related LigandHgitrl |
| Database Links | Reactome: R-HSA-5669034 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Tumor Necrosis Factor Ligand Superfamily Member 18 antibodyAnti-Activation-Inducible Tnf-Related Ligand antibodyAnti-Aitrl antibodyAnti-Glucocorticoid-Induced Tnf-Related Ligand antibodyAnti-Hgitrl antibodyAnti-TNFSF18 antibodyAnti-AITRL antibodyAnti-GITRL antibodyAnti-TL6 antibodyAnti-UNQ149 antibodyAnti-PRO175 antibody |
Information sourced from Uniprot.org