| Host: |
Rabbit |
| Applications: |
WB/IHC |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Tumor necrosis factor ligand superfamily member 14 (51-100 aa) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000IHC-P 1:50-300 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TNFSF14 |
| Gene ID: |
8740 |
| Uniprot ID: |
TNF14_HUMAN |
| Immunogen Region: |
51-100 aa |
| Specificity: |
LIGHT Polyclonal Antibody detects endogenous levels of LIGHT protein. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from the human TNF14 at the amino acid range 51-100 |
| Post Translational Modifications | N-glycosylated. The soluble form of isoform 1 derives from the membrane form by proteolytic processing. |
| Function | Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Acts as a ligand for TNFRSF14/HVEM. Upon binding to TNFRSF14/HVEM, delivers costimulatory signals to T cells, leading to T cell proliferation and IFNG production. |
| Protein Name | Tumor Necrosis Factor Ligand Superfamily Member 14Herpes Virus Entry Mediator LigandHvem-LHerpesvirus Entry Mediator LigandCd Antigen Cd258 Cleaved Into - Tumor Necrosis Factor Ligand Superfamily Member 14 - Membrane Form - Tumor Necrosis Factor Ligand Superfamily Member 14 - Soluble Form |
| Database Links | Reactome: R-HSA-5668541Reactome: R-HSA-5669034Reactome: R-HSA-5676594 |
| Cellular Localisation | Tumor Necrosis Factor Ligand Superfamily Member 14Membrane Form: Cell MembraneSingle-Pass Type Ii Membrane ProteinSoluble Form: SecretedIsoform 2: Cytoplasm |
| Alternative Antibody Names | Anti-Tumor Necrosis Factor Ligand Superfamily Member 14 antibodyAnti-Herpes Virus Entry Mediator Ligand antibodyAnti-Hvem-L antibodyAnti-Herpesvirus Entry Mediator Ligand antibodyAnti-Cd Antigen Cd258 Cleaved Into - Tumor Necrosis Factor Ligand Superfamily Member 14 - Membrane Form - Tumor Necrosis Factor Ligand Superfamily Member 14 - Soluble Form antibodyAnti-TNFSF14 antibodyAnti-HVEML antibodyAnti-LIGHT antibodyAnti-UNQ391 antibodyAnti-PRO726 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
