Immunofluorescence analysis of HeLa cells, using TNF14 Antibody. The picture on the right is blocked with the synthesized peptide.

Anti-TNFSF14 antibody (51-100 aa) (STJ93926)

SKU:
STJ93926
€60.00 - €315.00
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Host: Rabbit
Applications: WB/IHC
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Tumor necrosis factor ligand superfamily member 14 (51-100 aa) is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
IHC-P 1:50-300
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TNFSF14
Gene ID: 8740
Uniprot ID: TNF14_HUMAN
Immunogen Region: 51-100 aa
Specificity: LIGHT Polyclonal Antibody detects endogenous levels of LIGHT protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human TNF14 at the amino acid range 51-100
Post Translational Modifications N-glycosylated. The soluble form of isoform 1 derives from the membrane form by proteolytic processing.
Function Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Acts as a ligand for TNFRSF14/HVEM. Upon binding to TNFRSF14/HVEM, delivers costimulatory signals to T cells, leading to T cell proliferation and IFNG production.
Protein Name Tumor Necrosis Factor Ligand Superfamily Member 14
Herpes Virus Entry Mediator Ligand
Hvem-L
Herpesvirus Entry Mediator Ligand
Cd Antigen Cd258 Cleaved Into - Tumor Necrosis Factor Ligand Superfamily Member 14 - Membrane Form - Tumor Necrosis Factor Ligand Superfamily Member 14 - Soluble Form
Database Links Reactome: R-HSA-5668541
Reactome: R-HSA-5669034
Reactome: R-HSA-5676594
Cellular Localisation Tumor Necrosis Factor Ligand Superfamily Member 14
Membrane Form: Cell Membrane
Single-Pass Type Ii Membrane Protein
Soluble Form: Secreted
Isoform 2: Cytoplasm
Alternative Antibody Names Anti-Tumor Necrosis Factor Ligand Superfamily Member 14 antibody
Anti-Herpes Virus Entry Mediator Ligand antibody
Anti-Hvem-L antibody
Anti-Herpesvirus Entry Mediator Ligand antibody
Anti-Cd Antigen Cd258 Cleaved Into - Tumor Necrosis Factor Ligand Superfamily Member 14 - Membrane Form - Tumor Necrosis Factor Ligand Superfamily Member 14 - Soluble Form antibody
Anti-TNFSF14 antibody
Anti-HVEML antibody
Anti-LIGHT antibody
Anti-UNQ391 antibody
Anti-PRO726 antibody

Information sourced from Uniprot.org

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