| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:100-1:500IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TNFRSF17 |
| Gene ID: | 608 |
| Uniprot ID: | TNR17_HUMAN |
| Immunogen Region: | 1-100 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TNFRSF17 (NP_001183.2). |
| Immunogen Sequence: | MLQMAGQCSQNEYFDSLLHA CIPCQLRCSSNTPPLTCQRY CNASVTNSVKGTNAILWTCL GLSLIISLAVFVLMFLLRKI NSEPLKDEFKNTGSGLLGMA |
| Tissue Specificity | Expressed in mature B-cells, but not in T-cells or monocytes. |
| Function | Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 17B-Cell Maturation ProteinCd Antigen Cd269 |
| Database Links | Reactome: R-HSA-5669034 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Iii Membrane ProteinEndomembrane SystemPerinuclear Golgi-Like Structures |
| Alternative Antibody Names | Anti-Tumor Necrosis Factor Receptor Superfamily Member 17 antibodyAnti-B-Cell Maturation Protein antibodyAnti-Cd Antigen Cd269 antibodyAnti-TNFRSF17 antibodyAnti-BCM antibodyAnti-BCMA antibody |
Information sourced from Uniprot.org
