Anti-TNFRSF10C antibody (26-235) [S5220RM] (STJ11105220)

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STJ11105220
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Short Description :Rabbit monoclonal Tumor Necrosis Factor Receptor Superfamily Member 10c (26-235) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/ELISA
Host:Rabbit
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :S5220RM
Isotype:IgG
Conjugation:Unconjugated
Concentration:Lot specific
Purification:Affinity purification
Dilution Range:WB:1:500-1:1000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation:PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:TNFRSF10C
Gene ID:8794
Uniprot ID:TR10C_HUMAN
Immunogen Region:26-235
Immunogen Sequence:ATTARQEEVPQQTVAPQQQR HSFKGEECPAGSHRSEHTGA CNPCTEGVDYTNASNNEPSC FPCTVCKSDQKHKSSCTMTR DTVCQCKEGTFRNENSPEMC RKCSRCPSGEVQVSNCTSWD DIQCVEEFGANATVETPAAE ETMNTSPGTPAPAAEETMNT SPGTPAPAAEETMTTSPGTP APAAEETMTTSPGTPAPAAE ETMITSPGTP
Specificity:Recombinant fusion protein containing a sequence corresponding to amino acids 26-235 of human DcR1/CD263 (NP_003832.3).
Tissue Specificity Higher expression in normal tissues than in tumor cell lines. Highly expressed in peripheral blood lymphocytes, spleen, skeletal muscle, placenta, lung and heart.
Post Translational Modifications N-glycosylated and O-glycosylated.
Function Receptor for the cytotoxic ligand TRAIL. Lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. May protect cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand.
Protein Name Tumor Necrosis Factor Receptor Superfamily Member 10c
Antagonist Decoy Receptor For Trail/Apo-2l
Decoy Trail Receptor Without Death Domain
Decoy Receptor 1
Dcr1
Lymphocyte Inhibitor Of Trail
Tnf-Related Apoptosis-Inducing Ligand Receptor 3
Trail Receptor 3
Trail-R3
Trail Receptor Without An Intracellular Domain
Cd Antigen Cd263
Database Links Reactome: R-HSA-6803211
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Alternative Antibody Names Anti-Tumor Necrosis Factor Receptor Superfamily Member 10c antibody
Anti-Antagonist Decoy Receptor For Trail/Apo-2l antibody
Anti-Decoy Trail Receptor Without Death Domain antibody
Anti-Decoy Receptor 1 antibody
Anti-Dcr1 antibody
Anti-Lymphocyte Inhibitor Of Trail antibody
Anti-Tnf-Related Apoptosis-Inducing Ligand Receptor 3 antibody
Anti-Trail Receptor 3 antibody
Anti-Trail-R3 antibody
Anti-Trail Receptor Without An Intracellular Domain antibody
Anti-Cd Antigen Cd263 antibody
Anti-TNFRSF10C antibody
Anti-DCR1 antibody
Anti-LIT antibody
Anti-TRAILR3 antibody
Anti-TRID antibody
Anti-UNQ321 antibody
Anti-PRO366 antibody

Information sourced from Uniprot.org