| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Tumor necrosis factor alpha-induced protein 8 (31-80 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:10000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TNFAIP8 |
| Gene ID: | 25816 |
| Uniprot ID: | TFIP8_HUMAN |
| Immunogen Region: | 31-80 aa |
| Specificity: | TNF-IP 8 Polyclonal Antibody detects endogenous levels of TNF-IP 8 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human TFIP8 at the amino acid range 31-80 |
| Function | Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation. |
| Protein Name | Tumor Necrosis Factor Alpha-Induced Protein 8Tnf Alpha-Induced Protein 8Head And Neck Tumor And Metastasis-Related ProteinMdc-3.13Nf-Kappa-B-Inducible Ded-Containing ProteinNdedScc-S2Tnf-Induced Protein Gg2-1 |
| Database Links | Reactome: R-HSA-1483255 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Tumor Necrosis Factor Alpha-Induced Protein 8 antibodyAnti-Tnf Alpha-Induced Protein 8 antibodyAnti-Head And Neck Tumor And Metastasis-Related Protein antibodyAnti-Mdc-3.13 antibodyAnti-Nf-Kappa-B-Inducible Ded-Containing Protein antibodyAnti-Nded antibodyAnti-Scc-S2 antibodyAnti-Tnf-Induced Protein Gg2-1 antibodyAnti-TNFAIP8 antibody |
Information sourced from Uniprot.org