Anti-TNC antibody (Internal) (STJ71921)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-TNC (Internal) is suitable for use in ELISA research applications. |
| Applications | Pep-ELISA |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:8000.WB: Preliminary experiments in Human Skeletal Muscle, Placenta and Uterus lysates gave no specific signal but low background (at antibody concentration up to 1µg/ml). We would appreciate an |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | TNC |
| Gene ID | 3371 |
| Uniprot ID | TENA_HUMAN |
| Accession Number | NP_002151.2 |
| Immunogen Region | Internal |
| Immunogen Sequence | AEKGPQKSSTITAK |
Additional Info
| Function | Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6. In tumors, stimulates angiogenesis by elongation, migration and sprouting of endothelial cells. |
| Protein Name | TenascinTnCytotactinGmemGp 150-225Glioma-Associated-Extracellular Matrix AntigenHexabrachionJiMyotendinous AntigenNeuronectinTenascin-CTn-C |
| Database Links | Reactome: R-HSA-216083Reactome: R-HSA-3000170Reactome: R-HSA-3000178Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Names | Anti-Tenascin antibodyAnti-Tn antibodyAnti-Cytotactin antibodyAnti-Gmem antibodyAnti-Gp 150-225 antibodyAnti-Glioma-Associated-Extracellular Matrix Antigen antibodyAnti-Hexabrachion antibodyAnti-Ji antibodyAnti-Myotendinous Antigen antibodyAnti-Neuronectin antibodyAnti-Tenascin-C antibodyAnti-Tn-C antibodyAnti-TNC antibodyAnti-HXB antibody |
Information sourced from Uniprot.org