Anti-TNC antibody [81C6] (STJA0027462)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2bk
General Information
| Short Description | Mouse monoclonal Tenascin antibody for use in ELISA and FC in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/FC |
| Host | Mouse |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 81C6 |
| Isotype | IgG2bk |
| Conjugation | Unconjugated |
| Concentration | 1.18 mg/ml |
| Purification | Protein A/G purified from cell culture supernatant. |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | Tnc |
| Gene ID | 21923 |
| Uniprot ID | TENA_MOUSE |
Additional Info
| Post Translational Modifications | N-glycosylated. |
| Function | Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth when provided to neurons in culture. May play a role in supporting the growth of epithelial tumors. Ligand for integrins ITGA8:ITGB1, ITGA9:ITGB1, ITGAV:ITGB3 and ITGAV:ITGB6. In tumors, stimulates angiogenesis by elongation, migration and sprouting of endothelial cells. |
| Protein Name | TenascinTnHexabrachionTenascin-CTn-C |
| Database Links | Reactome: R-MMU-216083Reactome: -MMU-3000178Reactome: -MMU-381426Reactome: -MMU-8957275 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Names | Anti-Tenascin antibodyAnti-Tn antibodyAnti-Hexabrachion antibodyAnti-Tenascin-C antibodyAnti-Tn-C antibodyAnti-Tnc antibodyAnti-Hxb antibody |
Information sourced from Uniprot.org