Anti-TMT1B antibody (STJA0007371)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human METTL7B
General Information
| Short Description | Rabbit polyclonal anti-Thiol S-methyltransferase TMT1B for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TMT1B |
| Gene ID | 196410 |
| Uniprot ID | TMT1B_HUMAN |
| Immunogen | Synthesized peptide derived from human METTL7B |
| Specificity | This antibody detects endogenous levels of METTL7B at Human, Mouse, Rat |
Additional Info
| Function | Thiol S-methyltransferase that catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to alkyl and phenolic thiol-containing acceptor substrates. Together with TMT1B accounts for most of S-thiol methylation activity in the endoplasmic reticulum of hepatocytes. Selectively methylates S-centered nucleophiles from metabolites such as hydrogen sulfide and dithiothreitol. |
| Protein Name | Thiol S-Methyltransferase Tmt1bMethyltransferase-Like Protein 7bThiol S-Methyltransferase Mettl7b |
| Database Links | |
| Cellular Localisation | Endoplasmic Reticulum MembranePeripheral Membrane ProteinLipid DropletMicrosomeCytoplasmCytosolHighly Concentrated In The Perinuclear Area Of The Endoplasmic Reticulum (Er) And Surrounding Lipid DropletsMay Be Associated With The Specific Regions Of The Lr That Form Lipid Droplets And Targeted To The Initial Deposits Of Lipids Where The Lipid Droplets Form |
| Alternative Antibody Names | Anti-Thiol S-Methyltransferase Tmt1b antibodyAnti-Methyltransferase-Like Protein 7b antibodyAnti-Thiol S-Methyltransferase Mettl7b antibodyAnti-TMT1B antibodyAnti-METTL7B antibodyAnti-UNQ594 antibodyAnti-PRO1180 antibody |
Information sourced from Uniprot.org