| Host: |
Goat |
| Applications: |
Pep-ELISA/WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-TMPRSS4 (245-57) is suitable for use in ELISA and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
WB-0.3-1µg/mlELISA-antibody detection limit dilution 1:1000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
TMPRSS4 |
| Gene ID: |
56649 |
| Uniprot ID: |
TMPS4_HUMAN |
| Immunogen Region: |
245-57 |
| Accession Number: |
NP_063947.1; NP_001077416.1 |
| Specificity: |
This antibody is expected to recognise both reported isoforms (NP_063947.1 and NP_001077416.1). |
| Immunogen Sequence: |
HCFRKHTDVFNWK |
| Post Translational Modifications | Proteolytically processed.probably by an autocatalytic mechanism. |
| Function | Plasma membrane-anchored serine protease that directly induces processing of pro-uPA/PLAU into the active form through proteolytic activity. Seems to be capable of activating ENaC. (Microbial infection) In gut epithelial cells, facilitates human coronavirus SARS-CoV-2 infection through, at least, the cleavage of coronavirus spike glycoproteins which activates the glycoprotein for host cell entry. |
| Protein Name | Transmembrane Protease Serine 4Channel-Activating Protease 2Caph2Membrane-Type Serine Protease 2Mt-Sp2 Cleaved Into - Transmembrane Protease Serine 4 Catalytic Chain |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane ProteinTransmembrane Protease Serine 4 Catalytic Chain: SecretedActivated By Cleavage And Secreted |
| Alternative Antibody Names | Anti-Transmembrane Protease Serine 4 antibodyAnti-Channel-Activating Protease 2 antibodyAnti-Caph2 antibodyAnti-Membrane-Type Serine Protease 2 antibodyAnti-Mt-Sp2 Cleaved Into - Transmembrane Protease Serine 4 Catalytic Chain antibodyAnti-TMPRSS4 antibodyAnti-TMPRSS3 antibodyAnti-UNQ776 antibodyAnti-PRO1570 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
