Anti-TMPRSS3 antibody (405-454 aa) (STJ96047)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human TMPRSS3 at the amino acid range 405-454
General Information
| Short Description | Rabbit polyclonal anti-Transmembrane protease serine 3 (405-454 aa) for use in WB, IHC, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:10000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TMPRSS3 |
| Gene ID | 64699 |
| Uniprot ID | TMPS3_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human TMPRSS3 at the amino acid range 405-454 |
| Immunogen Region | 405-454 aa |
| Specificity | TMPRSS3 Polyclonal Antibody detects endogenous levels of TMPRSS3 protein. |
Additional Info
| Post Translational Modifications | Undergoes autoproteolytic activation. |
| Function | Probable serine protease that plays a role in hearing. Acts as a permissive factor for cochlear hair cell survival and activation at the onset of hearing and is required for saccular hair cell survival. Activates ENaC (in vitro). |
| Protein Name | Transmembrane Protease Serine 3Serine Protease Tadg-12Tumor-Associated Differentially-Expressed Gene 12 Protein |
| Database Links | |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Transmembrane Protease Serine 3 antibodyAnti-Serine Protease Tadg-12 antibodyAnti-Tumor-Associated Differentially-Expressed Gene 12 Protein antibodyAnti-TMPRSS3 antibodyAnti-ECHOS1 antibodyAnti-TADG12 antibodyAnti-UNQ323 antibodyAnti-PRO382 antibody |
Information sourced from Uniprot.org